Araguspongin B, CAS [[123000-02-2]] Preis auf Anfrage
Biozol Catalog Number:
BYT-ORB2299476
Supplier Catalog Number:
orb2299476
Alternative Catalog Number:
BYT-ORB2299476-50,BYT-ORB2299476-10
Manufacturer:
Biorbyt
Category:
Biochemikalien
Xestospongins and araguspongins, marine natural products originally isolated from sponges in the Pacific basin, exhibit vasodilatory effects. Inositol phosphates (IP) serve as crucial signal transduction messengers, activating IP3 receptors to facilitate Ca2+ release from intracellular stores. Araguspongin B specifically hinders the calcium-releasing function of inositol 1,4,5-trisphosphate at the receptor level within cerebral microsomes, demonstrating an inhibition concentration (IC50) of 0.6 µM. This potency places it nearly on par with xestospongin C in obstructing the IP3 receptors activity.
Molecular Weight:
446.7
CAS Number:
[123000-02-2]
Formula:
C28H50N2O2
Target:
Others
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