HDAC-IN-56, CAS [[2814571-89-4]] Preis auf Anfrage
Biozol Catalog Number:
BYT-ORB2566125
Supplier Catalog Number:
orb2566125
Alternative Catalog Number:
BYT-ORB2566125-10,BYT-ORB2566125-50
Manufacturer:
Biorbyt
Category:
Biochemikalien
HDAC-IN-56 ((S)-17b), an orally active inhibitor of class I histone deacetylase (HDAC), exhibits inhibitory constants (IC 50) of 56.0 6.0 nM for HDAC1, 90.0 5.9 nM for HDAC2, 422.2 105.1 nM for HDAC3, and greater than 10,000 nM for HDAC4-11. This compound displays robust antitumor activity, marked by its ability to significantly elevate intracellular acetylhistone H3 and P21 levels, while also inducing G1 cell cycle arrest and apoptosis effectively.
Molecular Weight:
485.55
CAS Number:
[2814571-89-4]
Formula:
C28H28FN5O2
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