Casopitant (GW679769) is an orally bioavailable neurokinin-1 (NK1) receptor antagonist investigated for the prevention of chemotherapy-induced (CINV) and postoperative nausea and vomiting (PONV). Its efficacy has been studied in both in vitro receptor binding assays and in vivo animal models of emesis.
Molecular Weight:
616.61
CAS Number:
[414910-27-3]
Formula:
C30H35F7N4O2
Target:
Neurokinin receptor,Cytochromes P450
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