N-Ac-gamma-Calicheamicin-AcBut-NHS ester, CAS [[174885-02-0]] Preis auf Anfrage

Product Overview

• Article Name: N-Ac-gamma-Calicheamicin-AcBut-NHS ester, CAS [[174885-02-0]] Preis auf Anfrage
• Biozol Catalog Number: BYT-ORB2814115
• Supplier Catalog Number: orb2814115
• Alternative Catalog Number: BYT-ORB2814115-10, BYT-ORB2814115-50
• Manufacturer: Biorbyt
• Category: Biochemikalien

Product Description

AcBut-N-Ac-gamma-Calicheamicin is a potent cytotoxic payload for antibody-drug conjugates (ADCs) that induces DNA double-strand breaks, leading to cell cycle arrest and apoptosis. Its application is prominent in cancer research, particularly for studying hematological malignancies like acute lymphoblastic leukemia (ALL) in both in vitro and in vivo models.

Product Properties

• Molecular Weight: 1779.73
• CAS Number: [174885-02-0]
• Formula: C77H99IN6O28S3
• Target: ADC Cytotoxin