Lipid C2 is an ionizable cationic lipid used to formulate mRNA-loaded LNPs that target the liver and spleen. In a CT26-EBV colon cancer model, LNPs with mRNA encoding EBV LMP-2, combined with anti-PD-1, reduced tumors and reversed T cell exhaustion, enhancing antigen-specific CD8+ T cell responses.
Molecular Weight:
1163.91
CAS Number:
[3003022-09-8]
Formula:
C70H142N6O6
Target:
Liposome
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