SHP2-IN-33, CAS [[2894017-46-8]] Preis auf Anfrage
Biozol Catalog Number:
BYT-ORB2814126
Supplier Catalog Number:
orb2814126
Alternative Catalog Number:
BYT-ORB2814126-10, BYT-ORB2814126-50
Manufacturer:
Biorbyt
Category:
Biochemikalien
SHP2-IN-33 (D13) is a potent allosteric SHP2 inhibitor with an enzymatic IC50 of 1.2 µM. It demonstrates anti-proliferative activity in vitro by inducing cell cycle arrest and apoptosis in Huh7 cells (IC50 = 38 µM) and shows significant in vivo efficacy in a Huh7 xenograft model with good oral bioavailability.
Molecular Weight:
384.33
CAS Number:
[2894017-46-8]
Formula:
C16H19Cl2N5S
Target:
Phosphatase,Apoptosis,MAPK
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