Nav1.7-IN-18 (Compound 31) is a potent and selective Nav1.7 channel blocker with a Ki of 4.9 nM. It demonstrates in vivo analgesic efficacy in a transgenic mouse model of inherited erythromelalgia, supporting its use in pain research.
Molecular Weight:
580.49
Formula:
C30H33Cl2F2NO4
Target:
Sodium Channel
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