Microtubule inhibitor 12 (Compound 2k) is a potent anti-proliferative agent that disrupts microtubule dynamics (IC50 = 22.23 µM), leading to G2/M phase arrest, apoptosis, and inhibited migration in cancer cells. It shows low micromolar IC50 values against multiple cancer cell lines (B16-F10, A549, HepG2, MCF-7) and exhibits in vivo antitumor activity in mouse models.
Molecular Weight:
390.44
Formula:
C22H22N4O3
Target:
Apoptosis,Microtubule Associated
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