Compound 22-Na is a potent, orally available, and intestine-restricted TGR5 agonist (EC50 < 1 µM). It is a valuable research tool for studying TGR5-mediated pathways in metabolic diseases, demonstrating glucose-lowering effects in murine models of diabetes.
Molecular Weight:
730.93
Formula:
C37H59N2NaO9S
Target:
Others,GPCR19
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