EGFR-IN-138 (compound 19) is a potent, small-molecule EGFR inhibitor demonstrating high potency against wild-type (IC50=37 nM), L858R mutant (IC50=2.6 nM), and T790M mutant (IC50=1.9 nM) kinases. This tool compound is suitable for in vitro biochemical and cellular assays in oncology research, particularly for studying resistance mechanisms in non-small cell lung cancer models.
Molecular Weight:
719.79
Formula:
C42H37N7O5
Target:
EGFR
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