NZ-804 is a potent, orally bioavailable inhibitor of the SARS-CoV-2 main protease (Mpro), demonstrating low nanomolar activity in vitro (IC50 8.9 nM, EC50 14 nM in HeLa-hACE2 cells). It shows broad-spectrum anti-coronavirus efficacy and has proven effective in reducing viral replication in mouse and hamster infection models.
Molecular Weight:
469.56
CAS Number:
[2858658-44-1]
Formula:
C27H23N3O3S
Target:
SARS-CoV,Virus Protease
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