JBJ-07-149, CAS [[2140807-58-3]] Preis auf Anfrage

Product Overview

• Article Name: JBJ-07-149, CAS [[2140807-58-3]] Preis auf Anfrage
• Biozol Catalog Number: BYT-ORB2814460
• Supplier Catalog Number: orb2814460
• Alternative Catalog Number: BYT-ORB2814460-10, BYT-ORB2814460-50
• Manufacturer: Biorbyt
• Category: Biochemikalien

Product Description

JBJ-07-149 is a potent, selective inhibitor of the EGFRL858R/T790M mutant (IC50 = 1.1 nM). It demonstrates anti-proliferative activity in Ba/F3 cells, with efficacy significantly enhanced in combination with Cetuximab. This compound is also a key chemical precursor for synthesizing the PROTAC molecule [DDC-01-163], supporting targeted protein degradation research.

Product Properties

• Molecular Weight: 510.61
• CAS Number: [2140807-58-3]
• Formula: C28H26N6O2S
• Target: EGFR