ZG-2033 (Compound 26) is a potent, orally bioavailable HIF-2alpha agonist with an EC50 of 490 nM in cellular reporter assays. It demonstrates anti-anemic activity in vivo and exhibits synergistic effects with other HIF-PH inhibitors like AKB-6548, making it a valuable research tool for investigating renal anemia and hypoxia signaling pathways.
Molecular Weight:
286.35
CAS Number:
[2685739-28-8]
Formula:
C15H14N2O2S
Target:
HIF/HIF Prolyl-Hydroxylase
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