AChE/BChE-IN-25 (Compound 6e) is a potent dual inhibitor of human acetylcholinesterase (IC50=7.9 nM) and equine butyrylcholinesterase (IC50=0.79 nM). It also functions as an antioxidant (IC50=22.91 µM) and has demonstrated neuroprotective effects in Drosophila and mouse models of cognitive impairment, showing promise for Alzheimers disease research.
Molecular Weight:
385.89
Formula:
C21H24ClN3O2
Target:
Cholinesterase (ChE)
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