Compound 3t (hDHODH-IN-16) is a potent and selective inhibitor of human dihydroorotate dehydrogenase, exhibiting an IC50 of 0.11 µM. It shows minimal cytotoxicity in healthy HaCaT cells (IC50 >200 µM), making it a valuable tool for in vitro research in immunology, oncology, and autoimmune disease studies targeting pyrimidine biosynthesis.
Molecular Weight:
296.36
Formula:
C18H20N2O2
Target:
Dehydrogenase,Others
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