Adhibin is a potent allosteric inhibitor of RhoGAP class IX myosin (Myo9), effectively suppressing its ATPase activity with IC50 values of ~2.5-2.6 µM. By disrupting motor function and RhoGTPase signaling, it is a valuable research tool for studying cellular processes like migration and adhesion in cancer metastasis research, applicable in both in vitro and in vivo experimental models.
Molecular Weight:
355.02
Formula:
C13H9Br2NO
Target:
Myosin
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