DS-003 is a BMS-378806 analog and small-molecule HIV-1 gp120 inhibitor targeting the CD4 binding site. Its antiviral activity is enhanced in prolonged or combination treatments but is impaired by soluble CD4 pre-exposure. This profile supports its investigation in pre-exposure prophylaxis and as a research tool for studying viral entry mechanisms in vitro.
Molecular Weight:
478.5
CAS Number:
[676489-50-2]
Formula:
C27H22N6O3
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