Isotenulin is a P-glycoprotein (P-gp) inhibitor that stimulates its ATPase activity to overcome multidrug resistance (MDR). It demonstrates cytotoxicity in both resistant (KB-vin) and sensitive (HeLaS3) cancer cell lines and acts synergistically with chemotherapeutics like Paclitaxel in vitro.
Molecular Weight:
306.354
CAS Number:
[10092-04-3]
Formula:
C17H22O5
Target:
P-gp
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