Pellotine is a natural alkaloid from Lophophora species that acts as a potent inverse agonist at the 5-HT7 receptor (EC50 291 nM) and exhibits high affinity for 5-HT1D and 5-HT6 receptors. It reduces intracellular cAMP, decreasing neuronal excitability, making it a valuable tool for in vitro studies of serotonin receptor signaling and neuropharmacology.
Molecular Weight:
237.295
CAS Number:
[19622-05-0]
Formula:
C13H19NO3
Target:
5-HT Receptor
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