Elsubrutinib (ABBV-105) is a potent, selective, and irreversible Brutons tyrosine kinase (BTK) inhibitor with an IC50 of 0.18 µM. This orally bioavailable small molecule is a valuable tool for investigating BTKs role in inflammatory and autoimmune disease pathways in both cellular and animal models.
Molecular Weight:
297.36
Purity:
99.77% (May vary between batches)
CAS Number:
[1643570-24-4]
Formula:
C17H19N3O2
Target:
BTK
Application Notes:
Solubility: DMSO:80.00 mg/mL (269.03 mM)
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