TCN 237 hydrochloride, CAS [[1784252-90-9]] Preis auf Anfrage

Product Overview

• Article Name: TCN 237 hydrochloride, CAS [[1784252-90-9]] Preis auf Anfrage
• Biozol Catalog Number: BYT-ORB3027411
• Supplier Catalog Number: orb3027411
• Alternative Catalog Number: BYT-ORB3027411-10, BYT-ORB3027411-50
• Manufacturer: Biorbyt
• Category: Biochemikalien

Product Description

TCN 237 serves as an antagonist of NR2B subunit-containing NMDA receptors, with a Ki value of 0.85 nM. It specifically blocks glutamate and glycine-induced currents in whole-cell patch-clamp assays when using L-M(TK-) cells expressing NR2B subunit-containing NMDA receptors. This is in contrast to its effect on L-M(TK-) cells with NR2A- or NR2D subunit-containing receptors and HEK293 cells with NR2C subunit-containing receptors. Additionally, TCN 237 at 3 mg/kg dosage mitigates carrageenan-induced mechanical hyperalgesia in rats.

Product Properties

• Molecular Weight: 412.33
• CAS Number: [1784252-90-9]
• Formula: C20H24Cl2FN3O
• Target: iGluR,Others