Carbonic anhydrase inhibitor32 (compound 5B) is an orally active, selective inhibitor of hCA (carbonic anhydrase) II/VII, with Ki values of 6.3 nM for hCA II, 10.1 nM for hCA VII, and 681 nM for hCA I. It shows potential for neuroprotection and anticonvulsant effects by reducing mTOR activation and increasing hippocampal KCC2 levels.
Molecular Weight:
384.41
Formula:
C17H16N6O3S
Target:
Na-K-Cl cotransporter,mTOR,Carbonic Anhydrase
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