GSK-3alpha/beta-IN-1, CAS [[1574354-24-7]] Preis auf Anfrage

Product Overview

• Article Name: GSK-3alpha/beta-IN-1, CAS [[1574354-24-7]] Preis auf Anfrage
• Biozol Catalog Number: BYT-ORB3027660
• Supplier Catalog Number: orb3027660
• Alternative Catalog Number: BYT-ORB3027660-10, BYT-ORB3027660-50
• Manufacturer: Biorbyt
• Category: Biochemikalien

Product Description

GSK-3alpha/beta-IN-1 is a GSK-3alpha/beta inhibitor with IC50 values of 0.265 µM for GSK-3alpha and 0.255 µM for GSK-3beta. It also inhibits PKA with an IC50 of 0.188 µM. GSK-3alpha/beta-IN-1 effectively reduces cell viability in three glioblastoma (GBM) cell lines (IC50: 3-6 µM over 72 hours) without being toxic to human astrocytes, and it exhibits good metabolic stability. Additionally, it shows potential central nervous system activity in a whole human blood-brain barrier (BBB) GBM model.

Product Properties

• Molecular Weight: 343.38
• CAS Number: [1574354-24-7]
• Formula: C21H17N3O2
• Target: GSK-3,PKA