PI3K-IN-58, CAS [[3067572-78-2]] Preis auf Anfrage

Product Overview

• Article Name: PI3K-IN-58, CAS [[3067572-78-2]] Preis auf Anfrage
• Biozol Catalog Number: BYT-ORB3027747
• Supplier Catalog Number: orb3027747
• Alternative Catalog Number: BYT-ORB3027747-10, BYT-ORB3027747-50
• Manufacturer: Biorbyt
• Category: Biochemikalien

Product Description

PI3K-IN-58 (Compound 17f) is an inhibitor of PI3Kalpha with an IC50 value of 0.039 µM. It shows significant antiproliferative effects on PC-3, 22RV1, MDA-MB-231, and MDA-MB-453 cell lines with IC50 values of 3.48 µM, 1.06 µM, 2.21 µM, and 0.93 µM, respectively. PI3K-IN-58 induces apoptosis by downregulating the expression of anti-apoptotic proteins Bcl-XL and Bcl-2 while upregulating the expression of the pro-apoptotic protein BAX. This compound is applicable for research in cancer targeting through PI3K pathways.

Product Properties

• Molecular Weight: 450.51
• CAS Number: [3067572-78-2]
• Formula: C22H22N6O3S
• Target: PI3K,Apoptosis,Bcl-2 Family