CBPD-409 is an orally active CBP/p300 degrader with a DC50 of 0.2-0.4 nM. It exhibits antiproliferative effects in AR+ prostate cancer cell lines VCaP, LNCaP, and 22Rv1, with an IC50 of 1.2-2.0 nM. Additionally, CBPD-409 shows antitumor activity.
Formula:
C46H52F2N10O5
Target:
Histone Acetyltransferase,PROTACs
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