YCH2823 is an inhibitor of USP7 (IC50= 49.6 nM, Kd= 0.117 µM) and demonstrates significant efficacy in suppressing both wild-type TP53 tumors and mutated tumors. It is approximately 5 times more potent than FT671, induces apoptosis, and exhibits a synergistic effect with mTOR inhibitors.
Formula:
C29H32N4O4
Target:
Apoptosis,DUB
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