HPK1-IN-45 (Compound 3) is an HPK1 inhibitor with an IC50 of 0.3 nM. It hinders the phosphorylation of SLP-76 (IC50= 57.52 nM) and the release of IL-2 (IC50= 38 nM). This compound is applicable in cancer research.
Formula:
C30H29N5O3
Target:
MAPK
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