RTx-161 is an allosteric Poltheta polymerase inhibitor with an IC50 value of 4.1 nM. It selectively kills HR-deficient cancer cells and inhibits PARP inhibitor (PARPi) resistance across various genetic backgrounds, including HR-proficient cells. RTx-161 also induces apoptosis.
Formula:
C21H18F7N3O4
Target:
Apoptosis,DNA/RNA Synthesis
* VAT and and shipping costs not included. Errors and price changes excepted
