SARS-CoV-2 Mpro-IN-23 (Compound 2) is an inhibitor of the SARS-CoV-2 main protease (Mpro), effective against both wild-type and mutant Mpro variants with an IC50 range of 0.057-0.92 µM. It also disrupts the late-stage entry of wild-type SARS-CoV-2 single-round infectious particles (SRIP) and inhibits viral replication of both the Mpro wild-type and its mutants, with an EC50 range of 0.02-0.52 µM.
Formula:
C54H84N2O20S2
Target:
SARS-CoV,Virus Protease
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