DW34, CAS [[2758171-54-7]] Preis auf Anfrage

Catalog Number: BYT-ORB3135173
Article Name: DW34, CAS [[2758171-54-7]] Preis auf Anfrage
Biozol Catalog Number: BYT-ORB3135173
Supplier Catalog Number: orb3135173
Alternative Catalog Number: BYT-ORB3135173-10, BYT-ORB3135173-50
Manufacturer: Biorbyt
Category: Biochemikalien
DW34 is an orally bioactive pan-BRD4-D1-biased inhibitor that also exhibits BRD4-D2 activity. It demonstrates a low nanomolar inhibitory effect comparable to I-BET151 (EC50 value of 0.16 µM), with an EC50 value of 0.14 µM. DW34 significantly alleviates lipopolysaccharide (LPS)-induced liver inflammation and acetaminophen (APAP)-induced toxicity by reducing chemokine expression and cell necrosis.
Molecular Weight: 434.58
CAS Number: [2758171-54-7]
Formula: C25H34N6O
Target: Epigenetic Reader Domain,Necroptosis