JAK3-IN-18, CAS [[2914873-59-7]] Preis auf Anfrage
Biozol Catalog Number:
BYT-ORB3136193
Supplier Catalog Number:
orb3136193
Alternative Catalog Number:
BYT-ORB3136193-10, BYT-ORB3136193-50
Manufacturer:
Biorbyt
Category:
Biochemikalien
JAK3-IN-18 is a selective and orally active dual inhibitor targeting JAK3 and TEC, with IC50 values of 0.5391 nM and 12.40 nM, respectively. It demonstrates remarkable selectivity for AK1, AK2, and TYK2, with selectivity ratios exceeding 10,000-fold. JAK3-IN-18 exhibits exceptional therapeutic efficacy in a mouse model of experimental autoimmune encephalomyelitis and is applicable for multiple sclerosis research.
Molecular Weight:
337.35
CAS Number:
[2914873-59-7]
Formula:
C18H16FN5O
Target:
JAK,Tyrosinase
* VAT and and shipping costs not included. Errors and price changes excepted