Conophyllidine, CAS [[152406-44-5]] Preis auf Anfrage
Biozol Catalog Number:
BYT-ORB3136380
Supplier Catalog Number:
orb3136380
Alternative Catalog Number:
BYT-ORB3136380-10, BYT-ORB3136380-50
Manufacturer:
Biorbyt
Category:
Biochemikalien
Conophyllidine is a bisindole alkaloid and functions as a selective inhibitor of M2 polarization. It inhibits histone acetylation by targeting the histone acetyltransferase domain of the P300/CBP proteins. The IC50 of Conophyllidine for IL-4-induced arginase inhibition is 0.31 µM. This compound effectively induces tumor-associated macrophages (TAMs) to shift from an anti-inflammatory to an inflammatory state, thereby enhancing the recruitment and function of cytotoxic CD8+ T cells in the tumor microenvironment. Conophyllidine is useful for studying tumor-associated macrophages.
Molecular Weight:
778.89
CAS Number:
[152406-44-5]
Formula:
C44H50N4O9
Target:
Arginase,Histone Acetyltransferase
* VAT and and shipping costs not included. Errors and price changes excepted
