JAK1-IN-18, CAS [[2459377-98-9]] Preis auf Anfrage

Catalog Number: BYT-ORB3136470
Article Name: JAK1-IN-18, CAS [[2459377-98-9]] Preis auf Anfrage
Biozol Catalog Number: BYT-ORB3136470
Supplier Catalog Number: orb3136470
Alternative Catalog Number: BYT-ORB3136470-10, BYT-ORB3136470-50
Manufacturer: Biorbyt
Category: Biochemikalien
JAK1-IN-18 (Example 2) is a selective JAK1 inhibitor with an IC50 value of 0.15 nM, demonstrating significantly greater inhibitory potency for JAK1 compared to JAK2 and JAK3. It significantly reduces inflammation in ulcerative colitis (UC) mouse models induced by DSS and Crohns disease (CD) rat models induced by DNBS. JAK1-IN-18 is applicable for research into autoimmune diseases (such as inflammatory bowel disease), viral infections (such as hepatitis B virus infection), and cancers (such as hematologic malignancies).
Molecular Weight: 366.37
CAS Number: [2459377-98-9]
Formula: C16H20F2N6O2
Target: JAK