AXT-914 is an inhibitor of the calcium-sensing receptor (CaSR). It exhibits antiviral activity against coronaviruses HCoV 229E and SARS-CoV2. AXT-914 reduces cytoplasmic calcium signaling activity caused by CaSR mutations. It is applicable in research on Bartter syndrome type 5, autosomal dominant hypocalcemia (ADH), and coronavirus infections.
Molecular Weight:
487.39
CAS Number:
[717104-43-3]
Formula:
C27H23BrN2O2
Target:
CaSR,SARS-CoV
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