YN14 (mixture of diastereomers), CAS [[3053689-54-3]] Preis auf Anfrage
Biozol Catalog Number:
BYT-ORB3136593
Supplier Catalog Number:
orb3136593
Alternative Catalog Number:
BYT-ORB3136593-10, BYT-ORB3136593-50
Manufacturer:
Biorbyt
Category:
Biochemikalien
YN14, a mixture of diastereomers, is a PROTAC (proteolysis-targeting chimera) specifically designed for the KRASG12C protein. It acts as an efficient and selective degrader of KRASG12C, forming a stable KRASG12C:YN14:VHL ternary complex with low binding free energy (deltaG). YN14 exhibits antiproliferative properties, significantly inhibiting the growth of cancer cells with the KRASG12C mutation.
Molecular Weight:
1156.39
CAS Number:
[3053689-54-3]
Formula:
C62H75F2N11O7S
Target:
PROTACs
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