Biotinylated Human BAFFR / TNFRSF13C Protein, His,

Product Overview

• Article Name: Biotinylated Human BAFFR / TNFRSF13C Protein, His,
• Biozol Catalog Number: BYT-ORB3158100
• Supplier Catalog Number: orb3158100
• Alternative Catalog Number: BYT-ORB3158100-200,BYT-ORB3158100-25
• Manufacturer: Biorbyt
• Category: Proteine/Peptide
• Species Reactivity: Human
• Conjugation: Biotin

Product Description

BAFF receptor (B-cell activating factor receptor, BAFF-R), also known as tumor necrosis factor receptor superfamily member 13C (TNFRSF13C), is a membrane protein of the TNF receptor superfamily which recognizes BAFF. B-cell activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of BAFF in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells.

Product Properties

• Molecular Weight: 10.3 kDa
• NCBI: 96
• Buffer: PBS, pH 7.4
• Purity: 90%
• Form: Powder
• Target: BAFFR

Application Notes

• Application Notes: Application Notes: This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (). The protein has a calculated MW of 10.3 kDa. The protein migrates as 12-13 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation