MitoPT TMRM Mitochondrial Depolarization Assay Kit

Catalog Number: BYT-ORB322260
Article Name: MitoPT TMRM Mitochondrial Depolarization Assay Kit
Biozol Catalog Number: BYT-ORB322260
Supplier Catalog Number: orb322260
Alternative Catalog Number: BYT-ORB322260-500
Manufacturer: Biorbyt
Category: Kits/Assays
The MitoPT TMRM Mitochondrial Depolarization Assay Kit detects mitochondrial membrane depolarization using the fluorescent dye TMRM. In healthy mitochondria with a negative charge due to polarization, TMRM accumulates and emits orange fluorescence. However, when the mitochondrial membrane potential collapses in apoptotic or metabolically stressed cells, the TMRM reagent disperses throughout the cell cytosol, resulting in a dramatic drop in fluorescence levels.