PBMC ((S)-1-Phenylethyl(2-aminoethyl)(4-(benzyloxy)-3-methoxybenzyl)carbamate), potent and selective inhibitor of TRPM8 channels. PBMC inhibits both chemical and thermal activation of TRPM8. Reverses the menthol and cold-induced facilitation of the micturition reflex.Represents a new lead for analgesic drugs based on blocking TRPM8.
Molecular Weight:
434.54
Purity:
>98%
Form:
powder
CAS Number:
[1352138-54-5]
Formula:
C26H30N2O4
Target:
Ion channel
Application Notes:
Solubility: Soluble in DMSO (up to 30 mg/ml). Biological Activity: TRPM8 blocker
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