Human SIRPA protein

Product Overview

• Article Name: Human SIRPA protein
• Biozol Catalog Number: BYT-ORB605248
• Supplier Catalog Number: orb605248
• Alternative Catalog Number: BYT-ORB605248-20,BYT-ORB605248-100,BYT-ORB605248-1
• Manufacturer: Biorbyt
• Category: Proteine/Peptide
• Alternative Names: Brain Ig-like molecule with tyrosine-based activation motifs (Bit) (CD172 antigen-like family member A) (Inhibitory receptor SHPS-1) (Macrophage fusion receptor) (MyD-1 antigen) (Signal-regulatory protein alpha-1) (Sirp-alpha-1) (Signal-regulatory protein alpha-2) (Sirp-alpha-2) (Signal-regulatory protein alpha-3) (Sirp-alpha-3) (p84) (CD_antigen: CD172a) (SHP substrate 1) (SHPS-1) (BIT) (MFR) (MYD1) (PTPNS1) (SHPS1) (SIRP)

Product Description

This Human SIRPA protein spans the amino acid sequence from region 31-370aa. Purity: Greater than 95% as determined by SDS-PAGE.

Product Properties

• Molecular Weight: 41.8 kDa
• UniProt: P78324
• Buffer: Lyophilized from a 0.2 µm filtered 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0
• Source: Homo sapiens (Human)
• Purity: Greater than 95% as determined by SDS-PAGE.
• Form: Lyophilized powder
• Sequence: EEELQVIQPDKSVLVAAGETATLRCTATSLIPVGPIQWFRGAGPGRELIYNQKEGHFPRVTTVSDLTKRNNMDFSIRIGNITPADAGTYYCVKFRKGSPDDVEFKSGAGTELSVRAKPSAPVVSGPAARATPQHTVSFTCESHGFSPRDITLKWFKNGNELSDFQTNVDPVGESVSYSIHSTAKVVLTREDVHSQVICEVAHVTLQGDPLRGTANLSETIRVPPTLEVTQQPVRAENQVNVTCQVRKFYPQRLQL

Application Notes

• Application Notes: Biological Origin: Homo sapiens (Human). Application Notes: Partial

Images

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Measured by its binding ability in a functional ELISA. Immobilized SIRPA at 2 µg/ml can bind human CD47, the EC50 of human SIRPA protein is 58.30-85.04 ng/ml.

Human SIRPA protein His/Myc tag captured on COOH chip can bind Human CD47 protein Fc tag with an affinity constant of 19.1 nM as detected by LSPR Assay.