AD10, KUZ, EC 3.4.24.81, A desintegrin and metalloprotease domain 10, mammalian disintegrinmetalloprotease, Kuzbanian protein homolog, CDw156c antigen
ADAM 10 is a member of the ADAM family of membraneanchored cell surface proteins, which contain both a disintegrin and a metalloprotease domain. ADAM 10 is expressed in a wide variety of tissues and resides on both the cell surface and within the cytoplasm. ADAM10 has been implicated in proteolytic release of a number of cell surface proteins in particular TNF alpha
