Clostridium aminobutyricum ferments 4-aminobutyrate to acetate and butyrate. One of the enzymes which catalyses this inter conversion of the intermediates is Gamma Hydroxybutyrate CoA Transferase. The amino acid sequence of the enzyme shows close relationships to proteins from the genomes of Clostridium difficile and Porphyromonas ginivalis. Characterisation of this enzyme from Clostridium aminobutyricum has shown it to be largely membrane bound, stable in anaerobic conditions.
