Recombinant Human CXCL12 (68AA)

Product Overview

• Article Name: Recombinant Human CXCL12 (68AA)
• Biozol Catalog Number: EBT-EPT140
• Supplier Catalog Number: EPT140
• Alternative Catalog Number: EBT-EPT140-10
• Manufacturer: ELK Biotechnology
• Category: Proteine/Peptide
• Alternative Names: Stromal Cell-Derived Factor 1, SDF-1, hSDF-1, C-X-C Motif Chemokine 12, Intercrine Reduced in Hepatomas, IRH, hIRH, Pre-B Cell Growth-Stimulating Factor, PBSF, CXCL12, SDF1, SDF1A, SDF1B

Product Description

Recombinant Human C-X-C Motif Chemokine 12 is produced by our E.coli expression system and the target gene encoding Lys22-Lys89 is expressed.

Product Properties

• Molecular Weight: Molecular weight: 8 KDa. Apparent molecular weight: 10 KDa, reducing conditions
• UniProt: P48061
• Purity: Greater than 95% as determined by reducing SDS-PAGE.

Application Notes

• Application Notes: Redissolve: Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100µg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.. Endotoxin: Less than 0.001 ng/µg (0.01 EU/µg) as determined by LAL test. Background: Stromal Cell-Derived Factor-1 (SDF-1) is a chemokine member of the intercrine family. SDF1 is expressed as five isoforms that differ only in the C terminal tail. SDF1alpha and SDF1beta are identical except for the four residues present in the C-terminus of SDF1beta but absent from SDF1alpha. SDF1 isoforms interact with CXCR4 and CXCR7 receptors on the cell surface, and can also bind syndecan4. SDF1 is known to influence lymphopoiesis, regulate patterning and cell number of neural progenitors, and promote angiogenesis. It also enhances the survival of myeloid progenitor cells