Recombinant Human PTH

Catalog Number: EBT-EPT146
Article Name: Recombinant Human PTH
Biozol Catalog Number: EBT-EPT146
Supplier Catalog Number: EPT146
Alternative Catalog Number: EBT-EPT146-50
Manufacturer: ELK Biotechnology
Category: Proteine/Peptide
Alternative Names: Parathyroid Hormone, PTH, Parathormone, Parathyrin
Recombinant Human Parathyroid Hormone is produced by our E.coli expression system and the target gene encoding Ser32-Gln115 is expressed.
Molecular Weight: Molecular weight: 9 KDa. Apparent molecular weight: 14 KDa, reducing conditions
UniProt: P01270
Purity: Greater than 95% as determined by reducing SDS-PAGE.
Application Notes: Redissolve: Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100µg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.. Endotoxin: Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test. Background: Parathyroid hormone is the most important endocrine regulator of calcium and phosphorus concentration in extracellular fluid. This hormone is secreted from cells of the parathyroid glands and finds its major target cells in bone and kidney. Another hormone, parathyroid hormone-related protein, binds to the same receptor as parathyroid hormone and has major effects on development. Like most other protein hormones, parathyroid hormone is synthesized as a preprohormone. After intracellular processing, the mature hormone is packaged within the Golgi into secretory vesicles, the secreted into blood by exocytosis. Parathyroid hormone is secreted as a linear protein of 84 amino acids