Recombinant Human NT-3

Catalog Number: EBT-EPT238
Article Name: Recombinant Human NT-3
Biozol Catalog Number: EBT-EPT238
Supplier Catalog Number: EPT238
Alternative Catalog Number: EBT-EPT238-50
Manufacturer: ELK Biotechnology
Category: Proteine/Peptide
Alternative Names: Neurotrophin-3, NT-3, HDNF, Nerve Growth Factor 2, NGF-2, Neurotrophic Factor, NTF3
Recombinant Human Neurotrophin-3 is produced by our E.coli expression system and the target gene encoding Tyr139-Thr257 is expressed.
Molecular Weight: Molecular weight: 13.6 KDa. Apparent molecular weight: 14 KDa, reducing conditions
UniProt: P20783
Purity: Greater than 95% as determined by reducing SDS-PAGE.
Application Notes: Redissolve: Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100µg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.. Endotoxin: Less than 0.001 ng/µg (0.01 EU/µg) as determined by LAL test. Background: Neurotrophin-3 (NT-3) is a member of the NGF family of neurotrophic factors and is structurally related to beta-NGF, BDNF and NT-4. The NT3 cDNA encodes a 257 amino acid residue precursor protein with a signal peptide and a proprotein that are cleaved to yield the 119 amino acid residue mature NT3.The amino acid sequences of mature human, murine and rat NT-3 are identical. NT-3 selectively promotes the differentiation and survival of specific neuronal subpopulations in both the central as well as the peripheral nervous systems