Recombinant Human FKBP4 (C-6His)

Product Overview

• Article Name: Recombinant Human FKBP4 (C-6His)
• Biozol Catalog Number: EBT-EPT273
• Supplier Catalog Number: EPT273
• Alternative Catalog Number: EBT-EPT273-50
• Manufacturer: ELK Biotechnology
• Category: Proteine/Peptide
• Alternative Names: Peptidyl-prolyl cis-trans isomerase FKBP4, 51kDa FK506-binding protein, 51kDa FK506-binding protein, 59kDa immunophilin, FK506-binding protein 4, FKBP59, HSP-binding immunophilin, immunophilin FKBP52, Rotamase, FKBP4

Product Description

Recombinant Human 52 kDa FK506 Binding Protein is produced by our E.coli expression system and the target gene encoding Met1-Ala459 is expressed with a 6His tag at the C-terminus.

Product Properties

• Molecular Weight: Molecular weight: 52.8 KDa. Apparent molecular weight: 50-60 KDa, reducing conditions
• UniProt: Q02790
• Purity: Greater than 95% as determined by reducing SDS-PAGE.

Application Notes

• Application Notes: Endotoxin: Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test. Background: FKBP4 act as a regulator of microtubule dynamics by inhibiting MAPT/TAU ability to promote microtubule assembly. FKBP4 may play a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors between cytoplasm and nuclear compartments, it also may have a protective role against oxidative stress in mitochondria. The isomerase activity controls neuronal growth cones via regulation of TRPC1 channel opening.