tumor protein p53(TP53) Homo sapiens This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546, 20937277). [provided by RefSeq, Feb 2013],
Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications.
Western Blot analysis of Jurkat cells using Acetyl-p53 (K370) Polyclonal Antibody. Antibody was diluted at 1:1000. Secondary antibody(catalog:RS0002) was diluted at 1:20000
Western Blot analysis of AD293 cells using Acetyl-p53 (K370) Polyclonal Antibody diluted at 1:1000. Secondary antibody(catalog:RS0002) was diluted at 1:20000
Immunohistochemical analysis of paraffin-embedded human-breast, antibody was diluted at 1:100
Immunohistochemical analysis of paraffin-embedded human-breast, antibody was diluted at 1:100
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