protein tyrosine kinase 2(PTK2) Homo sapiens This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene, but the full-length natures of only four of them have been determined. [provided by RefSeq, Oct 2015],
Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Western Blot analysis of various cells using Phospho-FAK (Y861) Polyclonal Antibody diluted at 1:1000
Western blot analysis of 3T3 HELA lysis using Phospho-FAK (Y861) antibody. Antibody was diluted at 1:1000
Enzyme-Linked Immunosorbent Assay (Phospho-ELISA) for Immunogen Phosphopeptide (Phospho-left) and Non-Phosphopeptide (Phospho-right), using FAK (Phospho-Tyr861) Antibody
Western blot analysis of lysates from HeLa cells, Jurkat cells and COS cells, using FAK (Phospho-Tyr861) Antibody. The lane on the right is blocked with the phospho peptide.
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