Synapsin I (phospho Ser9) rabbit pAb, Rabbit, Polyclonal

Product Overview

• Article Name: Synapsin I (phospho Ser9) rabbit pAb, Rabbit, Polyclonal
• Biozol Catalog Number: EBT-ES1410
• Supplier Catalog Number: ES1410
• Alternative Catalog Number: EBT-ES1410-50, EBT-ES1410-100
• Manufacturer: ELK Biotechnology
• Host: Rabbit
• Category: Antikörper
• Application: ELISA, IF, IHC, WB
• Species Reactivity: Human, Mouse, Rat
• Immunogen: The antiserum was produced against synthesized peptide derived from human Synapsin around the phosphorylation site of Ser9. AA range:3-52
• Alternative Names: SYN1, Synapsin-1, Brain protein 4.1, Synapsin I

Product Description

This gene is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. This member of the synapsin family plays a role in regulation of axonogenesis and synaptogenesis. The protein encoded serves as a substrate for several different protein kinases and phosphorylation may function in the regulation of this protein in the nerve terminal. Mutations in this gene may be associated with X-linked disorders with primary neuronal degeneration such as Rett syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008],

Product Properties

• Clonality: Polyclonal
• Concentration: 1 mg/ml
• Molecular Weight: 77kD
• NCBI: 6853
• UniProt: P17600

Application Notes

• Application Dilute: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.

Images

Western Blot analysis of various cells using Phospho-Synapsin I (S9) Polyclonal Antibody diluted at 1:1000

Western Blot analysis of 3T3 cells using Phospho-Synapsin I (S9) Polyclonal Antibody diluted at 1:1000

Western blot analysis of HELA KB 293T 3T3 lysis using Phospho-Synapsin I (S9) antibody. Antibody was diluted at 1:1000

Western blot analysis of lysates from 293 cells treated with PMA 200nM 30, using Synapsin (Phospho-Ser9) Antibody. The lane on the right is blocked with the phospho peptide.