NF-kappaB2 p100 (phospho-Ser866/870) rabbit pAb, Rabbit, Polyclonal

Product Overview

• Article Name: NF-kappaB2 p100 (phospho-Ser866/870) rabbit pAb, Rabbit, Polyclonal
• Biozol Catalog Number: EBT-ES14500
• Supplier Catalog Number: ES14500
• Alternative Catalog Number: EBT-ES14500-50, EBT-ES14500-100
• Manufacturer: ELK Biotechnology
• Host: Rabbit
• Category: Antikörper
• Application: WB
• Species Reactivity: Human, Mouse
• Immunogen: Synthesized phosho peptide around human NF-kappaB2 p100 (Ser866 and 870)
• Alternative Names: Nuclear factor NF-kappa-B p100 subunit (DNA-binding factor KBF2) (H2TF1) (Lymphocyte translocation chromosome 10 protein) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2) (Oncogene Lyt-10) (Lyt10) [Cleaved into: Nuclear factor NF-kappa-B p52 subunit]

Product Description

nuclear factor kappa B subunit 2(NFKB2) Homo sapiens This gene encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The protein encoded by this gene can function as both a transcriptional activator or repressor depending on its dimerization partner. The p100 full-length protein is co-translationally processed into a p52 active form. Chromosomal rearrangements and translocations of this locus have been observed in B cell lymphomas, some of which may result in the formation of fusion proteins. There is a pseudogene for this gene on chromosome 18. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013],

Product Properties

• Clonality: Polyclonal
• Concentration: 1 mg/ml
• Molecular Weight: 100kD
• NCBI: 4791
• UniProt: Q00653

Application Notes

• Application Dilute: WB 1:1000-2000

Images

Western Blot analysis of 1 MCF-7 treated with LPS, 2 MCF7,using primary antibody at 1:1000 dilution. Secondary antibody(catalog:RS23920) was diluted at 1:10000