Jak3 (phospho-Tyr980/981) rabbit pAb, Rabbit, Polyclonal

Product Overview

• Article Name: Jak3 (phospho-Tyr980/981) rabbit pAb, Rabbit, Polyclonal
• Biozol Catalog Number: EBT-ES15392
• Supplier Catalog Number: ES15392
• Alternative Catalog Number: EBT-ES15392-50, EBT-ES15392-100
• Manufacturer: ELK Biotechnology
• Host: Rabbit
• Category: Antikörper
• Application: IHC, WB
• Species Reactivity: Human, Mouse
• Immunogen: Synthesized phosho peptide around human Jak3 (Tyr980 and 981)
• Alternative Names: Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3) (Leukocyte janus kinase) (L-JAK)

Product Description

The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease). [provided by RefSeq, Jul 2008],

Product Properties

• Clonality: Polyclonal
• Concentration: 1 mg/ml
• Molecular Weight: 125kD
• NCBI: 3718
• UniProt: P52333

Application Notes

• Application Dilute: WB 1:500-2000,IHC-p 1:50-300

Images

Immunohistochemical analysis of paraffin-embedded human Squamous cell carcinoma of lung. 1, Antibody was diluted at 1:200(4 overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).